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Missouri Governor Parson Signs House Bill 3007, Missouri to

ST. LOUIS, July 15, 2022 (GLOBE NEWSWIRE) – Missouri Gov. Mike Parson at a ceremonial bill signing with the API Innovation Center (APIIC) @ Cortex on Thursday for House Bill (HB) 3007. The bill took effect on July 1, approving $ 15 million grant funding for advanced manufacturing of active pharmaceutical ingredients (APIs) and semiconductor computer chips. The passage of this bill is evidence of Missouri’s commitment to prioritizing bioscience innovation, health care, and advanced manufacturing and promoting job growth and economic growth across the state. .

The grants outlined in HB 3007 from the Missouri Technology Investment Fund will help fund the state’s efforts to strengthen domestic semiconductor production and lead the reshoring of APIs. According to the Food and Drug Administration (FDA), approximately 78 percent of active pharmaceutical ingredients (API) manufacturers are located outside the U.S. This state legislation combats the risk to public health and national security due to excess. national dependence on foreigners of foreign origin. manufacturers.

“This investment in advanced manufacturing of active pharmaceutical components and semiconductor computer chips will help strengthen our home supply chains and create quality jobs right here in Missouri,” said Governor Mike Parson. . “One of the greatest lessons we have learned from the COVID-19 pandemic and subsequent supply chain crisis, is our over-reliance on foreign manufacturing. In the next crisis, the last thing. what we want to do is rely on other countries for things we can – and do better – right here in Missouri. “

The United States Pharmacopeia (USP) has identified Missouri as the first in the nation to have the largest number of API manufacturers making essential medicines, positioning it as the ideal location to activate the process of reshoring drugs. US API APIIC @ Cortex is a nonprofit organization currently working with the Missouri API sector to strengthen American drug manufacturing. Their initiative was to establish Missouri as the nation’s hub for domestic API production, resulting in a secure U.S. drug supply chain.

“APIIC @ Cortex is proud to partner with the Governor and the state of Missouri to strengthen API in medicine in the United States,” said Tony Sardella, CEO and Chair of APIIC @ Cortex. “The Center’s efforts to promote the adoption of new and advanced manufacturing capabilities will help build health security in our country, reduce drug shortages and production costs while speeding up market time.”

Cortex President and CEO Sam Fiorello said, “APIIC @ Cortex brings together industry experts to advance new technologies and make the United States safer by gaining greater control. in our drug creating quality jobs that are accessible to the residents of our region.We welcome APIIC @ Cortex to the district and look forward to working with them towards a growing, diverse, and equitable economy in the region. “

APIIC @ Cortex’s initial project was to source the US-produced API for lomustine, a chemotherapy drug used to treat glioblastoma, an aggressive brain cancer. There is currently no U.S. source of lomustine, and recently the only manufacturer of the drug has significantly raised its price, making clinical trials expensive. In 2021, the manufacturer also discontinued the federal discount program for Medicare patients, leaving many patients struggling to pay for treatment. According to the Society for Neuro-Oncology, “the field of neuro-oncology is in the midst of a lomustine crisis.” This crisis was resolved by APIIC @ Cortex in partnership with the Glioblastoma Foundation, a nonprofit that will develop lomustine and make it cheaper and accessible for glioblastoma patients who need it most. Lomustine will be made using continuous flow manufacturing, an advanced drug manufacturing process made by Continuity Pharma that is more efficient than decades of batch manufacturing. The ongoing manufacturing process can improve drug quality, address shortages in essential drugs, speed up market time, and strengthen overall U.S. manufacturing competition.

“The Glioblastoma Foundation is proud to be part of this initiative to make Lomustine faster and cheaper for glioblastoma patients. We are grateful to our Continuity Pharma partners for sharing our commitment to bringing this drug to the people. who need it without overpricing because no one has to give up their chance at life for money, “said Gita Kwatra, PharmD and Chief Executive Officer of the Glioblastoma Foundation.

APIIC @ Cortex conducts stakeholder partnerships with key players, such as the Glioblastoma Foundation; Continuing Pharma; Emerson, Experitec, and Mallinckrodt Specialty Generics, to create a sustainable network for U.S. production of lomustine and other critical drugs.

Missouri Chamber of Commerce and Industry President and CEO Daniel Mehan stated, “There are strong national security and economic arguments being made today about the need for onshore high-tech manufacturing. Missouri-a leading state for to advance tech manufacturing-stands to benefit.Bringing these critical investments to Missouri will benefit every industry and bubble of our economy for decades to come.We thank Gov. Mike Parson and the leaders of Missouri General Assembly for helping position our state for this opportunity. ”

Brewer Science, headquartered in Rolla, Missouri, is a global leader in the tech industry, specializing in developing and manufacturing next-generation materials and processes that promote cutting-edge technology, including the semiconductor computer chips.

Brewer Science Executive Vice President Dan Brewer stated, “Brewer Science is living proof that Missouri is more than ready to be a hub for innovation in the semiconductor industry. For more than 40 years, the our business has helped develop Missouri’s growing, diverse high-tech talent pipeline and significant cost advantages that benefit all industries in our state.With these new critical investments, Missouri is ready and is poised to become a national leader in local semiconductor production. We are grateful for the leadership of Governor Mike Parson and all of the Missouri General Assembly who have promoted our growing industry. “

To learn more about APIIC @ Cortex and its commitment to risk elimination and protection of the nation’s API supply chain, visit: or contact For more information about Brewer Science and its work in technological innovation and the semiconductor industry, visit:

Media Questions:
Laura Reed, (618) 656-7333

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Figure 1: Signed by Missouri Gov. Mike Parson presented House Bill 3007 at the API Innovation Center @ Cortex Event

Signed by Missouri Gov. Mike Parson introduced House Bill 3007, which approves a $ 15 million grant fund for advanced manufacturing of active pharmaceutical ingredients (APIs) and semiconductor computer chips.

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  • Signed by Missouri Gov. Mike Parson presented House Bill 3007 at the API Innovation Center @ Cortex Event

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